Projects
CMV has a huge impact on the balance of our immune systems, even if we are healthy. As an example, 10-20% of all our T cells can be dedicated to [...]
The human immune system is a vast, interconnected network, yet most studies only look at one piece of the puzzle. Our lab is building a comprehensive systems-level map to predict [...]
Current antibody assays are akin to viewing the Earth from 30,000 feet: You can see the broad landscape, but not the fine details. We are bringing the view of the [...]
Influenza vaccine responses are highly heterogeneous, eliciting strong and durable immunity in some but little-to-no response in others. Our lab is bridging the gap between infant, adult, and elderly immunology [...]
As the mechanistic principles guiding tissue immunity unfold, the Reina Laboratory will focus on leveraging immune engineering technologies to enhance CD8 T cell functions in disease settings to unlock the [...]
Spatial transcriptomics at single-molecule resolution allows in situ measurements of hundreds to thousands of genes in large areas of tissues, allowing an unprecedented view into the secret life of TRM. [...]