Databases

The Cancer Epitope Database and Analysis Resource (CEDAR) is a freely available resource funded by NCI. It catalogs experimental data on antibody and T cell peptidic epitopes primarily studied in humans and non-human primates in the context of cancer disease. CEDAR also hosts tools to assist in the prediction and analysis of cancer epitopes. CEDAR is a companion site to the Immune Epitope Database (IEDB), which is funded by NIAID, and houses epitope data on infectious disease, allergy, autoimmunity and transplantation.

In 2014, the National Institutes of Health awarded a $4 million grant to La Jolla Institute to build an immune cell epigenome-database and make it freely available to researchers worldwide. The Database of Immune Cell Epigenomes (DICE) is designed to give researchers insights into how genes act within the immune system to set it in motion.

Created under a multi-million dollar competitive contract from the National Institutes of Health, the Immune Epitope Database (IEDB) contains information on how the immune system responds to a wide range of infectious organisms, allergy-causing substances and other things that stimulate the immune system. Rapidly emerging and persistent infectious diseases, such as Ebola, influenza, malaria and most recently, SARS-CoV-2, as well as ongoing bioterrorism concerns, make the epitope database a critical tool in the fight to improve and safeguard global public health.

A grant of over $17 million from the National Institute of Allergy and Infectious Diseases (NIAID), has established La Jolla Institute for Immunology (LJI) as the leading institute for human immunology data curation, analysis, and dissemination. With this funding, LJI has taken the helm of the Human Immunology Project Consortium Data Coordinating Center, a critical tool in the effort to fuel scientific collaboration in immunoprofiling and highlight findings from the overall Human Immunology Project Consortium (HIPC). The Peters lab at LJI joins co-leader, Professor Steven Kleinstein,Ph.D., at Yale School of Medicine, in leading and expanding the existing HIPC Data Coordinating Center website, called ImmuneSpace. They are building both a hub for HIPC information and a powerful analysis engine for scientists world wide. Scientists visiting the site can explore data from over 11,000 participants in 143 studies to generate new biological insights.