New research points to ‘stem-like’ T cells as culprits in ulcerative colitis
LJI scientists zero in on T cells that may drive autoimmune disease in human patients
The gut patrol
A fascinating new look at what drives T cells to guard the intestines
Amazing mucosa
“The whole mucosal immune system is so fascinating. It has to operate in an environment of extremes.”
Mucosal Immunology and IBD
A major area of research in our laboratory is the regulation of mucosal immunity. We have collaborated extensively with the
Kronenberg Lab
Mitchell Kronenberg,
Ph.D.
Professor, President Emeritus
Center for Autoimmunity and Inflammation, Center for Vaccine Innovation
Mitchell Kronenberg, Ph.D., and his team study T cells – white blood cells responsible for recognizing and responding to foreign invaders, such as microbes.
Cheroutre Lab
Hilde Cheroutre,
Ph.D.
Professor
Center for Autoimmunity and Inflammation, Center for Cancer Immunotherapy
Hilde Cheroutre, Ph.D., and her team study the development, function, and regulation of T lymphocytes, a type of white blood cells.
Dan Giles: Using AI to Improve Treatment of IBD
Inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis afflict over a million Americans. Currently, clinicians have to rely
LJI scientists flip molecular switches to distinguish closely related immune cell populations
LA JOLLA, CA—The cornerstone of genetics is the loss-of-function experiment. In short, this means that to figure out what exactly
LJI researchers gain new understanding of how neutrophils latch onto vessel walls to protect from infection and clean up injured tissue
LA JOLLA, CA—As an arm of the innate immune system, white blood cells called neutrophils form the first line of
Two LJI scientists selected to join the Mucosal Immunology Studies Team (MIST)
LA JOLLA, CA—Hilde Cheroutre, Ph.D., Professor and Division Head and Mitchell Kronenberg, Ph.D., President and Chief Scientific Officer, have been