Lab Kronenberg

Kronenberg

Mitchell Kronenberg

Portrait photo of Dr. Kronenberg. He is smiling at the camera

Ricardo Monterrosa
October 28, 2024

Kronenberg

Thomas Riffelmacher

Photo portrait of Tim Riffelmacher, Ph.D.

Ricardo Monterrosa
October 28, 2024

Kronenberg

Job Rocha

Ricardo Monterrosa
October 28, 2024

Kronenberg

Gabriel Ascui-Gac

Ricardo Monterrosa
October 28, 2024

Kronenberg

Cindy Luna

mtalbott
October 28, 2024

Croft, Kronenberg

Ann Janette Balancio

Ricardo Monterrosa
October 28, 2024

Research News

New research points to ‘stem-like’ T cells as culprits in ulcerative colitis

LJI scientists zero in on T cells that may drive autoimmune disease in human patients

Madeline McCurry-Schmidt
June 19, 2024

Kronenberg

Mechanisms for glycolipid antigen-driven cytokine polarization by Valpha14i NKT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

When insult is added to injury: crosstalk between ILCs and intestinal epithelium in IBD

Ricardo Monterrosa
June 6, 2024

Kronenberg

The Role of Invariant Natural Killer T Cells in Autoimmune Diseases

Ricardo Monterrosa
June 6, 2024

Kronenberg

Activation and function of iNKT and MAIT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Commensural microbiota and CD8+ T cells shape the formation of invariant NKT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Carbohdrate moieties as vaccine candidates: Meeting summary

Ricardo Monterrosa
June 6, 2024

Kronenberg

A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity

Ricardo Monterrosa
June 6, 2024

Kronenberg

Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice

Ricardo Monterrosa
June 6, 2024

Kronenberg

The role of invariant NKT cells at the interface of innate and adaptive immunity

Ricardo Monterrosa
June 6, 2024

Kronenberg

Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection

Ricardo Monterrosa
June 6, 2024

Kronenberg

Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

Regulatory T-cell stability and plasticity in mucosal and systemic immune systems

Ricardo Monterrosa
June 6, 2024

Kronenberg

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

Ricardo Monterrosa
June 6, 2024

Kronenberg

Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency

Ricardo Monterrosa
June 6, 2024

Kronenberg

Diverse endogenous antigens for mouse natural killer T cells: self-antigens that are not glycosphingolipids

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

Hepatic stellate cells function as regulatory bystanders

Ricardo Monterrosa
June 6, 2024

Kronenberg

Regulation of inflammation, autoimmunity, and infection immunity by HVEM-BTLA signaling

Ricardo Monterrosa
June 6, 2024

Kronenberg

Invariant NKT cells are required for ariway inflammation induced by house dust extracts

Ricardo Monterrosa
June 6, 2024

Kronenberg

Invariant natural killer T cells recognize glycolipids from pathogenic gram-positive bacteria

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg, Schoenberger

Mucosal memory CD8(+) T cells are selected in the periphery by an MHC class I molecure

Ricardo Monterrosa
June 6, 2024

Kronenberg

Cooling the fires of inflammation

Ricardo Monterrosa
June 6, 2024

Kronenberg

Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

Unique interplay between sugar and lipid in determining the antigenic potency of bacterial antigens for NKT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Glycolipids that elicit IFN-biased responses from natural killer T cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells

Ricardo Monterrosa
June 6, 2024

Kronenberg, Ley

Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans

Ricardo Monterrosa
June 6, 2024

Kronenberg

Making memory at birth: understanding the differentiation of natural killer T cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Intestinal mucus-derived nanoparticle-mediated activation of Wnt/β-catenin signaling plays a role in induction of liver natural killer T cell anergy in mice

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

Ricardo Monterrosa
June 6, 2024

Kronenberg

Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice

Ricardo Monterrosa
June 6, 2024

Kronenberg

Interruption of CXCL 13-CXCR5 axis increases upper genital tract pathology and activation of NKT cells following chlamydial genital infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg, Ley

Interleukin-27 receptor limits atherosclerosis in Ldlr-/- mice

Ricardo Monterrosa
June 6, 2024

Hedrick, Kronenberg

ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

A novel role for IL-27 in mediating the survival of activated mouse CD4 T lymphocytes

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

Ricardo Monterrosa
June 6, 2024

Kronenberg

HVEM: an unusual TNF receptor family member important for mucosal innate immune responses to microbes

Ricardo Monterrosa
June 6, 2024

Kronenberg

Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

Ricardo Monterrosa
June 6, 2024

Kronenberg

Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Production of α-galactosylceramide by a prominent member of the human gut microbiota

Ricardo Monterrosa
June 6, 2024

Kronenberg

A ‘GEM’ of a cell

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

BTLA interaction with HVEM expressed on CD8(+) T cells promotes survival and memory generation in response to a bacterial infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

The role of invariant natural killer T cells in microbial immunity

Ricardo Monterrosa
June 6, 2024

Kronenberg

Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Immunology: oiling the wheels of autoimmunity

Ricardo Monterrosa
June 6, 2024

Kronenberg

Escherichida coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in (NOD).B6 (Idd10/Idd18) mice

Ricardo Monterrosa
June 6, 2024

Kronenberg

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Transcriptional control of the development and function of Vα14i NKT cells.

Ricardo Monterrosa
June 6, 2024

Kronenberg

HVEM is a TNF receptor with multiple regulatory roles in the mucosal immune system

Ricardo Monterrosa
June 6, 2024

Benedict, Kronenberg

Distinct requirements of activation of NKT and NK cells during viral infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

Invariant natural killer T cells are depleted in renal impairment and recover after kidney transplantation

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

αβT cell receptors expressed by CD4(-)CD8αβ(-) intraepithelial T cells drive their fate into a unique lineage with unusual MHC reactivities

Ricardo Monterrosa
June 6, 2024

Kronenberg, Rao

Jarid2 is induced by TCR signalling and controls iNKT cell maturation

Ricardo Monterrosa
June 6, 2024

Kronenberg

Synthesis of a 2″-deoxy-β-GalCer

Ricardo Monterrosa
June 6, 2024

Kronenberg

Antigen-dependent versus -independent avtication of invariant NKT cells during infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

The tumor necrosis factor family member TNFSF14 (LIGHT) is required for resolution of intestinal inflammation in mice

Ricardo Monterrosa
June 6, 2024

Kronenberg

Transcriptional control of the development and function of Vα14i NKT cells

Ricardo Monterrosa
June 6, 2024

Altman, Kronenberg

Protein C-η controls CTLA-4-mediated regulatory T cell function

Ricardo Monterrosa
June 6, 2024

Hedrick, Kronenberg

IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset

Ricardo Monterrosa
June 6, 2024

Kronenberg

When less is more: T lymphocyte populations with restricted antigen receptor diversity

Ricardo Monterrosa
June 6, 2024

Kronenberg

Mucosal-resident T lymphocytes with invariant antigen receptors

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg, Schoenberger

Unique lamina propria stromal cells imprint the functional phenotype of mucosal dendritic cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg, Peters

IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis

Ricardo Monterrosa
June 6, 2024

Kronenberg

The alpha and omega of galactosylceramides in T cell immune function

Ricardo Monterrosa
June 6, 2024

Kronenberg

Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation

Ricardo Monterrosa
June 6, 2024

Kronenberg

Lipid and carbohydrate modifications of α-galactosylceramide differently influence mouse and human type I natural killer T cell activation

Ricardo Monterrosa
June 6, 2024

Kronenberg

Selective conditions are required for the induction of invariant NKT cell hyporesponsiveness by antigenic stimulation

Ricardo Monterrosa
June 6, 2024

Kronenberg

NKT10 cells: a novel iNKT cell subset

Ricardo Monterrosa
June 6, 2024

Kronenberg

A novel glycolipid antigen for NKT cells that preferentially induces IFN-γ production

Ricardo Monterrosa
June 6, 2024

Kronenberg

A new mouse strain for the analysis of invariant NKT cell function

Ricardo Monterrosa
June 6, 2024

Kronenberg

OMIP-030: Characterization of human T cell subsets via surfacr markers

Ricardo Monterrosa
June 6, 2024

Kronenberg

Phospholipid signals of microbial infection for the human immune system

Ricardo Monterrosa
June 6, 2024

Kronenberg

Invariant natural killer T cells: front line fighters in the war against pathogenic microbes

Ricardo Monterrosa
June 6, 2024

Kronenberg

CD1d-restricted peripheral T cell lymphoma in mice and humans

Ricardo Monterrosa
June 6, 2024

Hedrick, Kronenberg

ATP binding cassette transporter ABCA7 regulates NKT cell development and function by controlling CD1d expression and lipid raft content

Ricardo Monterrosa
June 6, 2024

Kronenberg

Murine corneal inflammation and nerve damage after infection with HSV-1 are promoted by HVEM and ameliorated by immune-modifying nanoparticle therapy

Ricardo Monterrosa
June 6, 2024

Kronenberg

MAITs onstage in mice and men with three acts for development

Ricardo Monterrosa
June 6, 2024

Kronenberg

Antigen specificity of invariant natural killer T-cells

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

Transcriptomes and metabolism define mouse and human mait cell populations

Ricardo Monterrosa
June 6, 2024

Kronenberg

Improved detection of cytokines produced by invariant NKT cells

Ricardo Monterrosa
June 6, 2024

Croft, Kawakami, Kronenberg

LIGHT-HVEM signaling in keratinocytes controls development of dermatitis

Ricardo Monterrosa
June 6, 2024

Kronenberg

Differential role of cathepsins S and B in hepatic APC-mediated NKT cell activation and cytokine secretion

Ricardo Monterrosa
June 6, 2024

Kronenberg

Development of asthma in inner-city children: possible roles of MAIT cells and variation in the home environment

Ricardo Monterrosa
June 6, 2024

Crotty, Hedrick, Kronenberg

Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

Ricardo Monterrosa
June 6, 2024

Cheroutre, Kronenberg

LIGHT-HVEM signaling in innate lymphoid cell subsets protects against enteric bacterial infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70

Ricardo Monterrosa
June 6, 2024

Kronenberg

Riboflavin metabolism variation among clinical isolates of streptococcus pneumoniae results in differential activation of MAIT cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Cancer immunity thwarted by the microbiome

Ricardo Monterrosa
June 6, 2024

Kronenberg

Role of MAIT cells in pulmonary bacterial infection

Ricardo Monterrosa
June 6, 2024

Kronenberg

Tissue-specific functions of invariant natural killer T cells

Ricardo Monterrosa
June 6, 2024

Kronenberg

Herpes simplex virus 1 latency and the kinetics of reactivation are regulated by a complex network of interactions between the herpesvirus entry mediator, its ligands (gD, BTLA, LIGHT, and CD160), and the latency-associated transcript

Ricardo Monterrosa
June 6, 2024

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