Immune cells may lead to more Parkinson’s cases in men
LJI scientists uncover autoimmune response that may help explain why Parkinson's disease is twice as common in male patients
Lab Lindestam Arlehamn
Nontuberculous mycobacteria and heterologous immunity to tuberculosis
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
Quantitative and Qualitative Perturbations of CD8 + MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals
T Cell Responses to Neural Autoantigens Are Similar in Alzheimer’s Disease Patients and Age-Matched Healthy Controls
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.
A mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-Guérin.
Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis
Corrigendum: Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis
Unaltered T cell responses to common antigens in individuals with Parkinson’s disease
M. tuberculosis antigen-responsive IL17 + CD4 T cells are disproportionately spared in ART-suppressed HIV
Antigen-specificity measurements are the key to understanding T cell responses
Identification of differentially recognized T cell epitopes in the spectrum of Mtb infection
A protective, single-visit TB vaccination regimen by co-administration of a subunit vaccine with BCG
The megapool approach to characterize adaptive CD4+ and CD8+ T cell responses
Combined antiviral therapy as effective and feasible option in allogenic hematopoietic stem cell transplantation during SARS-COV-2 infection: a case report
PINK1 is a target of T cell responses in Parkinson’s disease
Identification of differentially recognized T cell epitopes in the spectrum of tuberculosis infection
How T cells combat tuberculosis
By tracking T cell activity, researchers uncover promising tuberculosis vaccine and drug targets
Cecilia Lindestam Arlehamn wins WHAM Edge Award funding to study sex-based differences in Alzheimer’s and Parkinson’s diseases
Some neurological diseases show up more in men versus women. Researchers need to know why.
Immunologic defect may leave some vulnerable to rare bacterial infection
LJI scientists uncover defect that stops T cells from fighting MAC bacteria
Scientists uncover new targets for treating Parkinson’s disease
LJI study suggests therapies could stop T cells from attacking brain cells in Parkinson's
Tuberculosis
The aim of this work, in collaboration with Dr. Bjoern Peters, is to identify and characterize T cell epitopes from Mycobacterium tuberculosis in vaccination and active infection (NIH/NIAID, 75N93019C00067). We are also interested in defining human immune signatures of different…
Neurodegenerative Diseases
The aim of this work funded by Aligning Science Across Parkinson’s (ASAP), in collaboration with Dr. Alessandro Sette, is to investigate T cell reactivity and disease progression in Parkinson’s disease. We are also interested in characterizing T cell reactivity in…
Once upon a BCG vaccine
To fight tuberculosis, LJI scientists uncover the key immune cells in play after BCG vaccination
LJI scientists receive $3.5 million to investigate role of immune cells in Parkinson’s disease
More than 930,000 Americans are living with Parkinson's disease
LJI scientists link immune cells to Parkinson’s Disease onset
New research gives further evidence that autoimmunity plays a role in Parkinson’s disease
