The Decision Makers | Dr. Sam Myers x Global Autoimmune Institute
See how investment in science is reshaping the landscape of autoimmune disease research
Lab Myers
Central metabolism in Mycobacterium smegmatis during the transition from O2-rich to O2-poor conditions as studied by isotopomer-assisted metabolite analysis
Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol
Advances in analysis of microbial metabolic fluxes via (13)C isotopic labeling
Analysis of metabolic pathways and fluxes in a newly discovered thermophilic and ethanol-tolerant Geobacillus strain
Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells
Electron transfer dissociation (ETD): the mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein host cell factor C1
Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells
Human RNA Polymerase II Promoter Recruitment in Vitro Is Regulated by O-Linked N-Acetylglucosaminyltransferase (OGT)
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins
Specter: linear deconvolution for targeted analysis of data-independent acquisition mass spectrometry proteomics
Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling
Evaluation of Advanced Precursor Determination for Tandem Mass Tag (TMT)-Based Quantitative Proteomics across Instrument Platforms
Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits
SMAC mimetics promote NIK-dependent inhibition of CD4(+) T(H)17 cell differentiation
Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS
Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action
Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells
RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting
Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches
Novel antibodies for the simple and efficient enrichment of native O-GlcNAc modified peptides.
Proximity labeling in mammalian cells with TurboID and split-TurboID
Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias.
Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery.
OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis
Retron reverse transcriptase termination and phage defense are dependent on host RNase H1.
Mechanisms encoding STAT functional diversity for context-specific inflammatory responses.
Identification of RIOK2 as a master regulator of human blood cell development.
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response
Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor alpha determines t cell activation and function
A congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide
A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ
Stop. Rethink. Research.
LJI Research Technician Patrick Kennedy makes scientific breakthroughs in the Myers Lab
Researchers reveal how protein modifications power T cells
LJI scientists share a new, rapid method for studying phosphorylation and other post-translational modifications
LJI scientists solve the mystery of why OGT enzyme is critical for cell survival
New findings open door to better understanding cancers and many other diseases
Proteomics expert Sam Myers to join LJI faculty
Myers Lab to expand autoimmune disease research, cancer and more
