Stop. Rethink. Research.

May 16, 2024 Behind the Science

Stop. Rethink. Research.

LJI Research Technician Patrick Kennedy makes scientific breakthroughs in the Myers Lab

Apr 29, 2024 Research News

Researchers reveal how protein modifications power T cells

LJI scientists share a new, rapid method for studying phosphorylation and other post-translational modifications

Jan 31, 2024 bioRxiv

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Sepulveda H, Li X, Yue X, Carlos Angel J, Arteaga-Vazquez LJ, Brown C, Brunelli M, Jansz N, Puddu F, Scotcher J, Creed P, Kennedy P, Manriquez C, Myers SA, Crawford R, Faulkner GJ, Rao A

Dec 4, 2023 Nat Commun.

A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

Tao AJ, Jiang J, Gadbois GE, Goyal P, Boyle BT, Mumby EJ, Myers SA, English JG, Ferguson FM.

Sep 12, 2023 Immunity

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor alpha determines t cell activation and function

Larange A, Takazawa I, Kakugawa K, Thiault N, Ngoi S, Olive ME, Iwaya H, Seguin L, Vicente-Suarez I, Becart S, Verstichel G, Balancio A, Altman A, Chang JT, Taniuchi I, Lillemeier B, Kronenberg M, Myers SA, Cheroutre H

Aug 22, 2023 bioRxiv

A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

Tao AJ, Jiang J, Gadbois GE, Goyal P, Boyle BT, Mumby EJ, Myers SA, English JG, Ferguson FM.

Jun 19, 2023 Front Microbiol

Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system

Røyseth V, Hurysz BM, Kaczorowska AK, Dorawa S, Fedøy AE, Arsın H, Serafim MSM, Myers SA, Werbowy O, Kaczorowski T, Stokke R, O'Donoghue AJ, Steen IH.

Feb 1, 2023 Leukemia

Myers

Stop. Rethink. Research.

Researchers reveal how protein modifications power T cells

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor alpha determines t cell activation and function

A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response

OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response

LJI scientists solve the mystery of why OGT enzyme is critical for cell survival

Mechanisms encoding STAT functional diversity for context-specific inflammatory responses.