Lab Peters
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection
Epitope-specific airway-resident CD4+ T cell dynamics during experimental huyman RSV infection
The human immunopeptidone project: A roadmap to predict and treat immune diseases
A structured model for immune exposures
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
A sequence homology and bioinformatics approach can predict candidate tagets for immune responses in SARS-CoV-2
Candidate targets for immune responses to 2019-novel coronavirus (nCoV): sequence homology- and bioinformatic-based predictions
T cell epitope predictions
Identification of plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population
Proteome-wide Zika virus CD4 T cell epitope and HLA restriction determination. Immunohorizons
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B 100-Reactive CD4 + T-Regulatory Cells
Correction: Quantitative and qualitative perturbations of CD8+ MAITs in healthly Mycobacterium tuberculosis-infected individuals
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma
Quantitative and Qualitative Perturbations of CD8 + MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals
T cell responses to neural autoantigens are similar in Alzheimer’s disease patients and age-matched healthy controls
Lack of evidence supporting a role of IFN-b and TGF-b iin differential polarization of Bordetella pertussis specific-T cell responses
Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity
The TCR repertoire of a-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse.
Allele-specific thresholds of eluted ligands for T-cell epitope prediction.
Lack of evidence supporting a role of IFN-β and TGF-β in differential polarization of Bordetella pertussis specific-T cell responses.
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants.
Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction
Lack of evidence for BCG vaccine protection from severe COVID-19
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100-Reactive CD4(+) T-Regulatory Cells
B cells modulate mouse allergen-specific T cells in nonallergic laboratory animal-care workers.
Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases.
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection.
Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA-DQ2.5.
An immunologically friendly classification of non-peptidic ligands.
Functional analysis of immune signature genes in Th1* memory cells links ISOC1 and pyrimidine metabolism to IFN-g and IL-17 production.
TCRMatch: predicting T-cell receptor specificity based on sequence similarity to previously characterized receptors.
A system-view of Bordetella pertussis booster vaccination responses in adults primed with whole-cell versus acellular vaccine in infancy.
In vitro induction of neoantigen-specific T cells in myelodysplastic syndrome, a disease with low mutational burden.
Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals.
HLA-DR marks recently divided antigen-specific effector CD4 T cells in active tuberculosis patients.
SARS-CoV-2 human T cell epitopes: adaptive immune response against COVID-19.
Standardization of assay representation in the ontology for biomedical investigations.
OBO foundry in 2021: operationalizing open data principles to evaluate ontologies.
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: a global consortium study.
A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC.
NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data.
Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana.
Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria.
The cancer epitope database and analysis resource: a blueprint for the establishment of a new bioinformatics resource for use by the cancer immunology community.
Immunophenotyping assessment in a COVID-19 cohort (IMPACC): a prospective longitudinal study.
CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature.
Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease.
Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis
Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type–dependent effects of disease-risk variants
Towards the prediction of non-peptidic epitopes
Abacavir inhibits but does not cause self-reactivity to HLA-B*57:01-restricted EBV specific T cell receptors
Lack of evidence of significant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigensn- adaptive T cell responses in humans
Disruption of mitochondrial quality control genes promotes caspase-resistant cell survival following apoptotic stimuli
Linked CD4 + /CD8 + T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression
Distinguishing cell-cell complexes from dual lineage cells using single-cell transcriptomics is not trivial
A simple standard for sharing ontological mappings (SSSOM)
Bioinformatic analysis underpinning the frequent occurrence of immune thrombocytopenic purpura in COVID-19 patients
Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile
IEDB-3D 2.0: Structural data analysis within the Immune Epitope Database
Immunodominant T cell peptides from four candidate malarial antigens as biomarkers of protective immunity against malaria
The Cancer Epitope Database and Analysis Resource (CEDAR)
Impact of genetic polymorphisms on human immune cell gene expression
Cutting edge: transcriptional profiling reveals multifunctional and cytotoxic antiviral responses of zika virus-specific CD8+ T cells
Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles
Differential recognition of mycobacterium tuberculosis-specific epitopes as a function of tuberculosis disease history
Coronavirus Immunotherapeutic Consortium Database
Estimating tissue-specific peptide abundance from public RNA-Seq data
Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium
Identification of differentially recognized T cell epitopes in the spectrum of Mtb infection
Genome-wide characterization of T cell responses to Bordetella pertussis reveals broad reactivity and similar polarization irrespective of childhood vaccination profiles
Circulating T cell-monocyte complexes are markers of immune perturbations
Immunoinformatics: Predicting peptide-MHC binding
Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors
T cell reactivity to Bordetella pertussis is highly diverse regardless of childhood vaccination
Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients
IEDB and CEDAR: two sibling databases to serve the global scientific community
Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome
An integrated workflow to assess technical and biological variability of cell population frequencies in human peripheral blood by flow cytometry
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells
Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants
The megapool approach to characterize adaptive CD4+ and CD8+ T cell responses
A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps
Identification of cow milk epitopes to characterize and quantify disease-specific T cells in allergic children
Early antiviral CD4 and CD8 T cell responses are associated with upper respiratory tract clearance of SARS-CoV-2
A multi-omics systems vaccinology resource to develop and test computational models of immunity
Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology
Proteome Analysis for Inflammation Related to Acute and Convalescent Infection
Identification of differentially recognized T cell epitopes in the spectrum of tuberculosis infection
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
PEPMatch: a tool to identify short peptide sequence matches in large sets of proteins
Corrigendum to “Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study” [eBioMedicine 83 (2022) 104208]
Vac to the future
Vaccine researchers take on the challenge of predicting B. pertussis immunization outcomes
A step toward personalized immunotherapy for all
Scientists find evidence that all cancer patients mount an immune response to their tumors, suggesting that many more patients could benefit from personalized immunotherapy
New $17 million grant establishes LJI as global hub for immunology data curation and analysis
NIAID support opens gateway to new research into human immune responses to viruses, the development of autoimmune diseases, and more
LJI scientists reflect on what it means to make the “Highly Cited” list
A record number of LJI researchers have been named to the 2022 list, including two early career scientists
Graduate student Leila Chihab wins prestigious NSF grant
Chihab explores how T cells find and kill tumors
The Conrad Prebys Foundation grants more than $1.5 million to support critical infrastructure—and a fascinating branch of immunology
"This support allows LJI scientists to buy essential equipment and pursue fascinating early career research."
