This year’s nominee is Dr. Georg Schett, a TIME100 Health Pioneer recognized for his groundbreaking contributions to the field. Dr. Schett pioneered the application of CAR T-cell therapy to autoimmune diseases, particularly lupus, exemplifying the precise spirit of this award. Tireless, bold, and imbued with the kind of curiosity that changes lives, the research he has led has proven that durable remission is not a distant dream but a tangible reality. Studies he has led, which highlight the potential for long-term cures without immunosuppressive drugs, have expanded the horizons of treatment and reframed what is possible for patients devastated by autoimmune conditions. In bridging foundational science with clinical practice, Dr. Schett has taken the essential charge of medical research: to harness the power of discovery for humanity’s benefit, changing lives for the better.