Projects
As the mechanistic principles guiding tissue immunity unfold, the Reina Laboratory will focus on leveraging immune engineering technologies to enhance CD8 T cell functions in disease settings to unlock the [...]
Spatial transcriptomics at single-molecule resolution allows in situ measurements of hundreds to thousands of genes in large areas of tissues, allowing an unprecedented view into the secret life of TRM. [...]
Long-term tissue residency is a complex, context-dependent challenge requiring specific cellular adaptation strategies. Our recent work has identified common metabolic adaptations that empower CD8 T cell tissue residency and anti-tumor [...]
The aim of this work funded by Aligning Science Across Parkinson’s (ASAP), in collaboration with Dr. Alessandro Sette, is to investigate T cell reactivity and disease progression in Parkinson’s disease. [...]
The aim of this work, in collaboration with Dr. Bjoern Peters, is to identify and characterize T cell epitopes from Mycobacterium tuberculosis in vaccination and active infection (NIH/NIAID, 75N93019C00067). We [...]
In 2013, Dr. Vijayanand teamed up with Professor Christian Ottensmeier at the Cancer Center, University of Southampton, UK, to set up a large patient-centered cancer immunology program. Our work [...]
