Projects

As our knowledge of the FceRI-mediated signal transduction has grown for the last two decades, the need to study in vivo roles of this pathway in disease settings encouraged the [...]

T cells are central to almost all immune responses. The CD4 subset is capable of directing B cell responses and humoral immunity, and can modulate the actions of many other [...]

One large subgroup of these specialized T cells is encompassed by the IEL which are located in the epithelium of the small intestine in humans and mice. IEL are distinct [...]