Publications New

Jul 6, 2017 Nature

Identifying specificity groups in the T cell receptor repertoire

Glanville J, Huang H, Nau A, Hatton O, Wagar LE, Rubelt F, Ji X, Han A, Krams SM, Pettus C, Haas N, Arlehamn CSL, Sette A, Boyd SD, Scriba TJ, Martinez OM, Davis MM

Jul 5, 2017 Clin Vaccine Immunol

Waning immunity and microbial vaccines – workshop of the national institute of allergy and infectious diseases

Gu XX, Plotkin SA, Edwards KM, Sette A, Mills KHG, Levy O, Sant AJ, Mo A, Alexander W, Lu KT, Taylor CE

Jul 1, 2017 Nat Genet

Lineage-specific functions of TET1 in the postimplantation mouse embryo

Khoueiry R, Sohni A, Thienpont B, Luo X, Velde JV, Bartoccetti M, Boeckx B, Zwijsen A, Rao A, Lambrechts D, Koh KP

Jul 1, 2017 J Autoimmun

Alpha cells, the main source of IL-1β in human pancreas

Anquetil F, Sabouri S, Thivolet C, Rodriguez-Calvo T, Zapardiel-Gonzalo J, Amirian N, Schneider D, Castillo E, Lajevardi Y, von Herrath MG

Jul 1, 2017 J Immunol

Autoreactivity to sulfatide by human invariant NKT cells

Stax AM, Tuengel J, Girardi E, Kitano N, Allan LL, Liu V, Zheng D, Panenka WJ, Guillaume J, Wong CH, van Calenbergh S, Zajonc DM, van den Elzen P

Jul 1, 2017 J Immunol

Bolstering the number and function of HSV-1-specific CD8(+) effector memory T cells and tissue-resident memory T cells in latently infected trigeminal ganglia reduces recurrent ocular herpes infection and disease

Khan AA, Srivastava R, Chentoufi AA, Kritzer E, Chilukuri S, Garg S, Yu DC, Vahed H, Huang L, Syed SA, Furness JN, Tran TT, Anthony NB, McLaren CE, Sidney J, Sette A, Noelle RJ, BenMohamed L

Jul 1, 2017 Antiviral Res

Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists

Shiryaev SA, Farhy C, Pinto A, Huang CT, Simonetti N, Ngono AE, Dewing A, Shresta S, Pinkerton AB, Cieplak P, Strongin AY, Terskikh AV

Jul 1, 2017 Lancet Gastroenterol Hepatol

Epitiope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomized, double-blind, placebo-controlled phase I studies

Goel G, King T, Daveson AJ, Andrews JM, Krishnarajah J, Krause R, Brown GJE, Fogel R, Barish CF, Epstein R, Kinney TP, Miner Jr PB, Tye-Din JA, Girardin A, Taavela J, Popp A, Sidney J, Maki M, Goldstein KE, Griffin PH, Wang S, Dzuris JL, Williams LJ, Sette A, Zavier RJ, Sollid LM, Jabri B, Anderson RP

Jul 1, 2017 Nat Immunol

The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection

Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW

Jun 29, 2017 Nature

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A

Jun 27, 2017 Sci Rep

Galactosylsphingamides: new α-GalCer analogues to probe the F’-pocket of CD1d

Guillaume J, Wang J, Janssens J, Remesh SG, Risseeuw MDP, Decruy T, Froeyen M, Elewaut D, Zajonc DM, Calenbergh SV

Jun 21, 2017 BMC Immunol

Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes

Paul S, Arlehamn CSL, Schulten V, Westernberg L, Sidney J, Peters B, Sette A