Publications New

Nov 30, 2021 Cell Rep.

Heterogeneity of human anti-viral immunity shaped by virus, tissue, age, and sex.

Poon MML, Byington E, Meng W, Kubota M, Matsumoto R, Grifoni A, Weiskopf D, Dogra P, Lam N, Szabo PA, Ural BB, Wells SB, Rosenfeld AM, Brusko MA, Brusko TM, Connors TJ, Sette A, Sims PA, Luning Prak ET, Shen Y, Farber DL.

Nov 22, 2021 Cardiovasc Res.

Heterogeneity of immune cells in human atherosclerosis revealed by scRNA-Seq.

Vallejo J, Cochain C, Zernecke A, Ley K.

Nov 19, 2021 Sci Immunol.

TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy.

Gupta RK, Gracias DT, Figueroa DS, Miki H, Miller J, Fung K, Ay F, Burkly L, Croft M.

Nov 19, 2021 Sci Immunol.

SARS-CoV-2 infection generates tissue-localized immunological memory in humans.

Poon MML, Rybkina K, Kato Y, Kubota M, Matsumoto R, Bloom NI, Zhang Z, Hastie KM, Grifoni A, Weiskopf D, Wells SB, Ural BB, Lam N, Szabo PA, Dogra P, Lee YS, Gray JI, Bradley MC, Brusko MA, Brusko TM, Saphire EO, Connors TJ, Sette A, Crotty S, Farber DL.

Nov 19, 2021 Nat Commun.

COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types.

Schmiedel BJ, Rocha J, Gonzalez-Colin C, Bhattacharyya S, Madrigal A, Ottensmeier CH, Ay F, Chandra V, Vijayanand P.

Nov 18, 2021 Nat Commun.

A mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-Guérin.

Woodworth JS, Clemmensen HS, Battey H, Dijkman K, Lindenstrøm T, Salvador Laureano R, Taplitz R, Morgan J, Aagaard C, Rosenkrands I, Lindestam Arlehamn CS, Andersen P, Mortensen R.

Nov 17, 2021 Clin Infect Dis.

Robust T cell responses in anti-CD20 treated patients following COVID-19 vaccination: a prospective cohort study.

Madelon N, Lauper K, Breville G, Sabater Royo I, Goldstein R, Andrey DO, Grifoni A, Sette A, Kaiser L, Siegrist CA, Finckh A, Lalive PH, Didierlaurent AM, Eberhardt CS.

Nov 12, 2021 Sci Immunol.

Immune signatures underlying post-acute COVID-19 lung sequelae.

Cheon IS, Li C, Son YM, Goplen NP, Wu Y, Cassmann T, Wang Z, Wei X, Tang J, Li Y, Marlow H, Hughes S, Hammel L, Cox TM, Goddery E, Ayasoufi K, Weiskopf D, Boonyaratanakornkit J, Dong H, Li H, Chakraborty R, Johnson AJ, Edell E, Taylor JJ, Kaplan MH, Sette A, Bartholmai BJ, Kern R, Vassallo R, Sun J.

Nov 10, 2021 Front Immunol.

High frequencies of functional virus-specific CD4 + T cells in SARS-CoV-2 subjects with olfactory and taste disorders.

Mele D, Calastri A, Maiorano E, Cerino A, Sachs M, Oliviero B, Mantovani S, Baldanti F, Bruno R, Benazzo M, Grifoni A, Sette A, Mondelli MU, Varchetta S.

Nov 10, 2021 Cell Host Microbe.

Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner.

Keeton R, Richardson SI, Moyo-Gwete T, Hermanus T, Tincho MB, Benede N, Manamela NP, Baguma R, Makhado Z, Ngomti A, Motlou T, Mennen M, Chinhoyi L, Skelem S, Maboreke H, Doolabh D, Iranzadeh A, Otter AD, Brooks T, Noursadeghi M, Moon JC, Grifoni A, Weiskopf D, Sette A, Blackburn J, Hsiao NY, Williamson C, Riou C, Goga A, Garrett N, Bekker LG, Gray G, Ntusi NAB, Moore PL, Burgers W.

Nov 9, 2021 Front Immunol.

Recognition of variants of concern by antibodies and T cells induced by a SARS-CoV-2 inactivated vaccine.

Melo-González F, Soto JA, González LA, Fernández J, Duarte LF, Schultz BM, Gálvez NMS, Pacheco GA, Ríos M, Vázquez Y, Rivera-Pérez D, Moreno-Tapia D, Iturriaga C, Vallejos OP, Berríos-Rojas RV, Hoppe-Elsholz G, Urzúa M, Bruneau N, Fasce RA, Mora J, Grifoni A, Sette A, Weiskopf D, Zeng G, Meng W, González-Aramundiz JV, González PA, Abarca K, Ramírez E, Kalergis AM, Bueno SM.

Nov 9, 2021 J Virol.

Identification and characterization of Rift Valley fever virus-specific T cells reveals a dependence on CD40/CD40L interactions for prevention of encephalitis.

Barbeau DJ, Cartwright HN, Harmon JR, Spengler JR, Spiropoulou CF, Sidney J, Sette A, McElroy AK.