Role of T cell in allergy and Asthma

 

Selected References

1. Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, Shu Liang, Bjoern Peters, Alessandro Sette, Vijayanand P (2020). Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma. Science Immunology. 2020 Jun 12;5(48):eaba6087. doi: 10.1126/sciimmunol.aba6087. PMID: 32532832. PMCID: PMC7372639.
2. Seumois, G., Zapardiel-Gonzalo, J., White, B., Singh, D., Schulten, V., Dillon, M., Hinz, D., Broide, D.H, Sette, A., Peters, B., Vijayanand, P (2016). Transcriptional profiling of Th2 cells identifies pathogenic features associated with asthma. Journal of Immunology. PMCID: PMC4936908
3. Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L, Vedanayagam M, Ganesan AP, Chawla A, Djukanović R, Ansel KM, Peters B, Rao A, Vijayanand P. (2014). Epigenomic analysis of primary human T cells reveals novel enhancers associated with Th2 memory differentiation and asthma susceptibility. Nature Immunology 15(8):777-88. PMCID: PMC4140783

 

Grants

NIH/NHLBI UG1HL139117, San Diego Team Asthma Management using Phenotypes (STAMP)

NIH/NIAID U19AI135731, LJI Epitope Validation Center: Characterization of epitope-specific T cells responding to food, fungal and inner-city allergens

NIH/NIAID R01AI121426, Epigenome-wide association study of childhood asthma

NIH/NHLBI R01HL114093, Epigenetics of severe asthma