Publications

All Altman Ay Benedict Cheroutre Croft Crotty Einav Eschweiler Grifoni Hedrick Hogan Kawakami Kronenberg Ley Lindestam Lisdestam Arlehamn Myers Pandurangan Peters Rao Reina Saphire Schmiedel Schoenberger Sette Seumois Sharma Shresta Vijayanand Von Herrath Weiskopf

Dec 31, 2021

MAbs.

Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large scale synthetic phage libraries.

Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, Mucker EM, Fouch ME, Davidson E, Doranz BJ, Kailasan S, Aman MJ, Li H, Hooper JW, Saphire EO, Crowe JE, Liu Q, Axelrod F, Sato AK.

Dec 17, 2021

Elife.

5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.

Stoyanova E, Riad M, Rao A, Heintz N.

Dec 17, 2021

Nat Commun.

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment.

Dinh HQ, Pan F, Wang G, Huang QF, Olingy CE, Wu ZY, Wang SH, Xu X, Xu XE, He JZ, Yang Q, Orsulic S, Haro M, Li LY, Huang GW, Breunig JJ, Koeffler HP, Hedrick CC, Xu LY, Lin DC, Li EM.

Jan 19, 2018

Sci Immunol

Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis

Patil VS, Madrigal A, Schmiedel BJ, Clarke J, O’Rourke P, de Silva AD, Harris E, Peters B, Seumois G, Weiskopf D, Sette A, Vijayanand P

Dec 10, 2021

Sci Adv.

Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.

Rodrigues KA, Rodriguez-Aponte SA, Dalvie NC, Lee JH, Abraham W, Carnathan DG, Jimenez LE, Ngo JT, Chang JYH, Zhang Z, Yu J, Chang A, Nakao C, Goodwin B, Naranjo CA, Zhang L, Silva M, Barouch DH, Silvestri G, Crotty S, Love JC, Irvine DJ.

Dec 10, 2021

Sci Adv

Phosphate-mediated co-anchoring of RBD immunogens and molecular adjuvants to alum 4 potentiates humoral immunity against SARS-CoV-2

Dec 06, 2021

J Exp Med.

HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.

Liu W, Chou TF, Garrett-Thomson SC, Seo GY, Fedorov E, Ramagopal UA, Bonanno JB, Wang Q, Kim K, Garforth SJ, Kakugawa K, Cheroutre H, Kronenberg M, Almo SC.

Dec 03, 2021

Sci Immunol.

A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.

Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ.

Dec 03, 2021

Science.

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern.

Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D’Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O, UPenn COVID Processing Unit, Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Prak ETL, Greenplate AR, Wherry EJ.

Dec 01, 2021

Nat Nanotechnol.

Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety.

Nguyen NT, Huang K, Zeng H, Jing J, Wang R, Fang S, Chen J, Liu X, Huang Z, You MJ, Rao A, Huang Y, Han G, Zhou Y.

Dec 01, 2021

Cell Res.

Novel attempts launched toward universal sarbecovirus vaccine.

Li H, Saphire EO.

Dec 01, 2021

Clin Microbiol Infect.

The potential clinical utility of measuring severe acute respiratory syndrome coronavirus 2-specific T-cell responses.

Goletti D, Petrone L, Manissero D, Bertoletti A, Rao S, Ndunda N, Sette A, Nikolayevskyy V.