Publications

Oct 8, 2024 bioRxiv

Heterozygosity for neurodevelopmental disorder-associated trio variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice

Ishchenko Y, Jeng AT, Feng S, Nottoli T, Manriquez-Rodriguez C, Nguyen KK, Carrizales MG, Vitarelli MJ, Corcoran EE, Greer CA, Myers SA, Koleske AJ

Aug 20, 2024 Nat Commun

Riok2 transcriptionally regulates tric and dyskerin complexes to prevent telomere shortening

Ghosh S, Nguyen MT, Choi HE, Stahl M, Kuhn AL, Van der Auwera S, Grabe HJ, Volzke H, Homuth G, Myers SA, Hogaboam CM, Noth I, Martinez FJ, Petsko GA, Glimcher LH

Aug 13, 2024 ACS Omega

Clickable probes for pathogen proteasomes: Synthesis and applications

Liu LJ, Lucero B, Manriquez-Rodriguez C, Francisco KR, Teixeira TR, Yohannan DJ, Ballatore C, Myers SA, O'Donoghue AJ, Caffrey CR

Jun 4, 2024 Dev Cell

Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity

Yu SB, Wang H, Sanchez RG, Carlson NM, Nguyen K, Zhang A, Papich ZD, Abushawish AA, Whiddon Z, Matysik W, Zhang J, Whisenant TC, Ghassemian M, Koberstein JN, Stewart ML, Myers SA, Pekkurnaz G

Jun 1, 2024 Nat Methods

Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput

Kennedy PH, Alborzian Deh Sheikh A, Balakar M, Jones AC, Olive ME, Hegde M, Matias MI, Pirete N, Burt R, Levy J, Little T, Hogan PG, Liu DR, Doench JG, Newton AC, Gottschalk RA, de Boer CG, Alarcón S, Newby GA, Myers SA

Jan 31, 2024 bioRxiv

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Sepulveda H, Li X, Yue X, Carlos Angel J, Arteaga-Vazquez LJ, Brown C, Brunelli M, Jansz N, Puddu F, Scotcher J, Creed P, Kennedy P, Manriquez C, Myers SA, Crawford R, Faulkner GJ, Rao A

Dec 4, 2023 Nat Commun.

A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

Tao AJ, Jiang J, Gadbois GE, Goyal P, Boyle BT, Mumby EJ, Myers SA, English JG, Ferguson FM.

Sep 12, 2023 Immunity

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor alpha determines t cell activation and function

Larange A, Takazawa I, Kakugawa K, Thiault N, Ngoi S, Olive ME, Iwaya H, Seguin L, Vicente-Suarez I, Becart S, Verstichel G, Balancio A, Altman A, Chang JT, Taniuchi I, Lillemeier B, Kronenberg M, Myers SA, Cheroutre H

Aug 22, 2023 bioRxiv

A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

Tao AJ, Jiang J, Gadbois GE, Goyal P, Boyle BT, Mumby EJ, Myers SA, English JG, Ferguson FM.

Jun 19, 2023 Front Microbiol

Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system

Røyseth V, Hurysz BM, Kaczorowska AK, Dorawa S, Fedøy AE, Arsın H, Serafim MSM, Myers SA, Werbowy O, Kaczorowski T, Stokke R, O'Donoghue AJ, Steen IH.

Feb 1, 2023 Leukemia

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response

Jutzi JS, Marneth AE, Jiménez-Santos MJ, Hem J, Guerra-Moreno A, Rolles B, Bhatt S, Myers SA, Carr SA, Hong Y, Pozdnyakova O, van Galen P, Al-Shahrour F, Nam AS, Mullally A.

Feb 1, 2023 Leukemia

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response

Jutzi JS, Marneth AE, Jiménez-Santos MJ, Hem J, Guerra-Moreno A, Rolles B, Bhatt S, Myers SA, Carr SA, Hong Y, Pozdnyakova O, van Galen P, Al-Shahrour F, Nam AS, Mullally A.