Publications

Oct 3, 2024 Cell

Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography

Watanabe R, Zyla D, Parekh D, Hong C, Jones Y, Schendel SL, Wan W, Castillon G, Saphire EO

Oct 1, 2024 EBioMedicine

Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice

Verma SK, Ana-Sosa-Batiz F, Timis J, Shafee N, Maule E, Pinto PBA, Conner C, Valentine KM, Cowley DO, Miller R, Elong Ngono A, Tran L, Varghese K, Dos Santos Alves RP, Hastie KM, Saphire EO, Webb DR, Jarnagin K, Kim K, Shresta S.

Jul 26, 2024 ACS Cent Sci

Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation

Shaw JB, Harvey SR, Du C, Xu Z, Edgington RM, Olmedillas E, Saphire EO, Wysocki VH

Jul 24, 2024 bioRxiv

HLA topography enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

Killian JT, Glenn King R, Lucander ACK, Kizziah JL, Fucile CF, Diaz-Avalos R, Qiu S, Silva-Sanchez A, Mousseau BJ, Macon KJ, Callahan AR, Yang G, Emon Hossain M, Akther J, Good DB, Kelso S, Houp JA, Rosenblum F, Porrett PM, Ong SC, Kumar V, Saphire EO, Kearney JF, Randall TD, Rosenberg AF, Green TJ, Lund FE

Jul 18, 2024 ACS Omega

Development of a Crystallographic Screening to Identify Sudan Virus VP40 Ligands

Werner AD, Krapoth N, Norris MJ, Heine A, Klebe G, Saphire EO, Becker S

Jul 17, 2024 mBio

Cellular endosomal potassium ion flux regulates arenavirus uncoating during virus entry

Shaw AB, Tse HN, Byford O, Plahe G, Moon-Walker A, Hover SE, Saphire EO, Whelan SPJ, Mankouri J, Fontana J, Barr JN

Jun 28, 2024 Science

A neutralizing antibody prevents postfusion transition of measles virus fusion protein

Zyla DS, Della Marca R, Niemeyer G, Zipursky G, Stearns K, Leedale C, Sobolik EB, Callaway HM, Hariharan C, Peng W, Parekh D, Marcink TC, Diaz Avalos R, Horvat B, Mathieu C, Snijder J, Greninger AL, Hastie KM, Niewiesk S, Moscona A, Porotto M, Ollmann Saphire E

Mar 11, 2024 Front Immunol

Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers

Bricio-Moreno L, Barreto de Albuquerque J, Neary JM, Nguyen T, Kuhn LF, Yeung Y, Hastie KM, Landeras-Bueno S, Olmedillas E, Hariharan C, Nathan A, Getz MA, Gayton AC, Khatri A, Gaiha GD

Mar 9, 2024 bioRxiv

Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation

Shaw J, Harvey S, Du C, Xu Z, Olmedillas E, Saphire EO, Wysocki VH

Dec 15, 2023 bioRxiv

Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation

Olmedillas E, Rajamanickam RR, Avalos RD, Sosa FA, Zandonatti MA, Harkins SS, Shresta S, Hastie KM, Saphire EO

Nov 28, 2023 Cell Rep

The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus

Yu X, Hastie KM, Davis CW, Avalos RD, Williams D, Parekh D, Hui S, Mann C, Hariharan C, Takada A, Ahmed R, Saphire EO

Nov 17, 2023 bioRxiv

Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers

Moreno LB, de Albuquerque JB, Neary JM, Nguyen T, Hastie KM, Landeras-Bueno S, Hariharan C, Nathan A, Getz MA, Gayton AC, Khatri A, Gaiha GD, Saphire EO, Luster AD, Moon JJ