Publications

Oct 1, 2024 EBioMedicine

Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice

Verma SK, Ana-Sosa-Batiz F, Timis J, Shafee N, Maule E, Pinto PBA, Conner C, Valentine KM, Cowley DO, Miller R, Elong Ngono A, Tran L, Varghese K, Dos Santos Alves RP, Hastie KM, Saphire EO, Webb DR, Jarnagin K, Kim K, Shresta S.

Jun 21, 2024 mSphere

Gemykibivirus detection in acute encephalitis patients from Nepal

Tuladhar ET, Shrestha S, Vernon S, Droit L, Mihindukulasuriya KA, Tamang M, Karki L, Elong Ngono A, Jha B, Awal BK, Chalise BS, Jha R, Shresta S, Wang D, Manandhar KD.

Jun 5, 2024 bioRxiv

Genomic sequencing and neutralizing serological profiles during acute dengue infection: A 2017 cohort study in Nepal

Prajapati S, Ngono AE, Cauley MM, Timis J, Shrestha S, Bastola A, Mandal SK, Yadav SR, Napit R, Moi ML, Yamabhai M, Sessions OM, Shresta S, Manandhar KD.

Jun 3, 2024 bioRxiv

Dengue Virus Surveillance in Nepal Yields the First On-Site Whole Genome Sequences of Isolates from the 2022 Outbreak

Napit R, Ngono AE, Mihindukulasuriya KA, Pradhan A, Khadka B, Shrestha S, Droit L, Paredes A, Karki L, Khatiwada R, Tamang M, Chalise BS, Rawal M, Jha B, Wang D, Handley SA, Shresta S, Manandhar KD.

Feb 15, 2024 medRxiv

Gemykibivirus detection in acute encephalitis patients from Nepal

Tuladhar ET, Shrestha S, Vernon S, Droit L, Mihindukulasuriya KA, Tamang M, Karki L, Ngono AE, Jha B, Awal BK, Chalise BS, Jha R, Shresta S, Wang D, Manandhar KD.

Dec 15, 2023 bioRxiv

Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation

Olmedillas E, Rajamanickam RR, Avalos RD, Sosa FA, Zandonatti MA, Harkins SS, Shresta S, Hastie KM, Saphire EO

May 30, 2023 Cell Rep

Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence

Hastie KM, Yu X, Ana-Sosa-Batiz F, Zyla DS, Harkins SS, Hariharan C, Wasserman H, Zandonatti MA, Miller R, Maule E, Kim K, Valentine KM, Shresta S, Saphire EO

Apr 1, 2023 Antiviral Res

SARS-CoV-2 Omicron (B.1.1.529) shows minimal neurotropism in a double-humanized mouse model

Alves RPDS, Wang YT, Mikulski Z, McArdle S, Shafee N, Valentine KM, Miller R, Verma SK, Batiz FAS, Maule E, Nguyen MN, Timis J, Mann C, Zandonatti M, Alarcon S, Rowe J, Kronenberg M, Weiskopf D, Sette A, Hastie K, Saphire EO, Festin S, Kim K, Shresta S

Sep 12, 2022 Nat Commun

SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.

Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, Rich JN, Spector DH, Benner C, Shresta S, Carlin AF.

May 9, 2022 Pathogens

Acute-phase serum cytokine levels and correlation with clinical outcomes in children and adults with primary and secondary dengue virus infection in Myanmar between 2017 and 2019.

Nwe KM, Ngwe Tun MM, Myat TW, Sheng Ng CF, Htun MM, Lin H, Hom NS, Soe AM, Elong Ngono A, Hamano S, Morita K, Thant KZ, Shresta S, Thu HM, Moi ML.

Apr 12, 2022 Cell Rep

A zika virus mutation enhances transmission potential and confers escape from protective dengue virus immunity.

Regla-Nava JA, Wang YT, Fontes-Garfias CR, Liu Y, Syed T, Susantono M, Gonzalez A, Viramontes KM, Verma SK, Kim K, Landeras-Bueno S, Huang CT, Prigozhin DM, Gleeson JG, Terskikh AV, Shi PY, Shresta S.

Nov 1, 2021 Antiviral Res.

SARS-CoV-2 monoclonal antibodies with therapeutic potential: Broad neutralizing activity and No evidence of antibody-dependent enhancement.

Wang YT, Allen RD 3rd, Kim K, Shafee N, Gonzalez AJ, Nguyen MN, Valentine KM, Cao X, Lu L, Pai CI, Johnson S, Kerwin L, Zhou H, Zhang Y, Shresta S.