Mar 25, 2016 Science
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen
Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I, Hu X, Spencer S, Jones M, Georgeson E, Adachi Y, Kubitz M, decamp AC, Julien J-P, Wilson IA, Burton DR, Crotty S, Schief WR
Mar 8, 2016 Proc Natl Acad Sci USA
CXCL13 is a plasma biomarker of germinal center activity
Havenar-Daughton C, Lindqvist M, Heit A, Wu JE, Reiss SM, Kendric K, Bélanger S, Kasturi SP, Landais E, Akondy RS, McGuire HM, Bothwell M, Vagefi PA, Scully E, IAVI Protocol C Principal Investigators, Tomaras GD, Davis MM, Poignard P, Ahmed R, Walker BD, Pulendran B, McElrath MJ, Kaufmann DE, Crotty S
Mar 1, 2016 J Immunol
Cutting edge: NFAT transcription factors promote the generation of follicular helper T cells in response to acute viral infection
Martinez GJ, Hu JK, Pereira RM, Crampton JS, Togher S, Bild N, Crotty S, Rao A
Jan 14, 2016 PLoS Pathog
Broadly neutralizing antibody responses in a large longitudinal sub-Saharan HIV primary infection cohort
Landais E, Huang Z, Havenar-Daughton C, Murrell B, Price MA, Wickramasinghe L, Ramos A, Bian CB, Simek M, Allen S, Karita E, Kilembe W, Lakhi S, Inambao M, Kamali A, Sanders EJ, Anzala O, Edward V, Bekker LG, Tang J, Gilmour J, Kosakovsky-Pond SL, Phung P, Wrin T, Crotty S, Godzik A, Poignard P
Dec 1, 2015 Journal of Immunology
Reversible reprogramming of circulating memory T follicular helper cell function during chronic HIV infection
Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F, He Z, Metcalf T, Ghneim K, Locci M, Ancuta P. Routy JP, Trautmann L, Li Y, McDermott AB, Koup RA, Petrovas C, Migueles SA, Connors M, Tomaras GD, Moir S, Crotty S, Haddad EK
Dec 1, 2015 Cell
Immunogenicity of stabilized HIV-1 envelope trimmers with reduced exposure of non-neutralizing epitopes
de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW
Oct 1, 2015 Journal of Virology
Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity
Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I, Stanfield R, Ward AB, Burton DR, Klasse PJ, Sanders RW, Moore JP, Crotty S
Oct 1, 2015 Proceedings of the National Academy of Sciences of the United States of America
Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3
Nance JP, Bélanger S, Johnston RJ, Hu JK, Takemori T, Crotty S
Sep 1, 2015 Nature Immunology
LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6
Choi YS, Gullicksrud JA, Xing S, Zeng Z, Shan Q, Li F, Love PE, Peng W, Xue HH, Crotty S
Sep 1, 2015 PLoS Pathogens
Structural and functional characterization of anti-A33 antibodies reveal a potent cross-species orthopoxviruses neutralizer
Matho MH, Schlossman A, Meng X, Benhnia MR, Kaever T, Buller M, Doronin K, Parker S, Peters B, Crotty S, Xiang Y, Zajonc DM
Aug 1, 2015 Proceedings of the National Academy of Sciences of the United States of America
Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with portective immunity
Weiskopf D, Bangs DJ, Sidney J, Kolla RV, De Silva AD, de Silva AM, Crotty S, Peters B, Sette A