Publications

Jul 22, 2020 Sci Adv.

Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.

Dhanwani R, Takahashi M, Mathews IT, Lenzi C, Romanov A, Watrous JD, Pieters B, Hedrick CC, Benedict CA, Linden J, Nilsson R, Jain M, Sharma S.

Jan 23, 2020 Gastroenterology

Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution

Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T

Oct 15, 2018 Nat Commun

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae

Chandra S, Gray J, Kiosses WB, Khurana A, Hitomi K, Crosby CM, Chawla A, Fu Z, Zhao M, Veerapen N, Richardson SK, Porcelli SA, Besra G, Howell AR, Sharma S, Peters B, Kronenberg M

Jul 12, 2018 PLoS Pathog

DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection

Loureiro ME, Zorzetto-Fernandes AL, Radoshitzky S, Chi X, Dallari S, Marooki N, Lèger P, Foscaldi S, Harjono V, Sharma S, Zid BM, López N, de la Torre JC, Bavari S, Zúñiga E

Feb 1, 2018 Curr Opin Immunol

Cytosolic sensing of immuno-stimulatory DNA, the enemy within

Dhanwani R, Takahashi M, Sharma S

Jan 19, 2018 Nat Commun

Binding of NUFIP2 to roquin promotes recognition and regulation of ICOS mRNA

Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoggmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V

Aug 12, 2016 J Virol

cGAS-STING signaling regulates initial innate control of cytomegalovirus infection

Lio CJ, McDonald B, Takahashi M, Dhanwani R, Sharma N, Huang J, Pham E, Benedict CA, Sharma S

Jun 20, 2016 Gut

The TRAP1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1

Bertin S, Aoki-Nonaka Y, Lee J, de Jong PR, Kim P, Han T, Yu T, To K, Takahashi N, Boland BS, Chang JT, Ho SB, Herdman S, Corr M, Franco A, Sharma S, Dong H, Akopian AN, Raz E

Aug 1, 2014 Immunity

In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation

Chen R, Bélanger S, Frederick MA, Li B, Johnston RJ, Xiao N, Liu YC, Sharma S, Peters B, Rao A, Crotty S, Pipkin ME

Jul 1, 2013 Nature

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry

Sharma S, Quintana A, Findlay GM, Mettlen M, Baust B, Jain M, Nilsson R, Rao A, Hogan PG