Publications

Jan 1, 2020 J Biosci

TET methylcytosine oxidases: new insights from a decade of research

Lio CJ, Yue X, Lopez-Moyado IF, Tahiliani M, Aravind L, Rao A.

Sep 30, 2019 Nat Rev Immunol

Defining ‘T cell exhaustion’

Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugil E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D

Sep 3, 2019 Biochemistry

Unusual activity of a Chlamydomonas TET/JBP family enzyme

Aravind L, Balasubramanian R, Rao A

Aug 29, 2019 Blood

Dysregulation of the TET family of epigenetic regulators in hematopoietic malignancies

Lio CJ, Yuita H, Rao A

Aug 20, 2019 Proc Natl Acad Sci U S A

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation

Lopez-Moyado IF, Tsagaratou A, Yuita H, Seo H, Delatte B, Heinz S, Benner C, Rao A

Jul 1, 2019 Nat Struct Mol Biol

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition

Halabelian L, Ravichandran M, Li Y, Zeng H, Rao A, Aravind L, Arrowsmith CH

Jun 18, 2019 Proc Natl Acad Sci U S A

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion

Seo H, Chen J, González-Avalos E, Samaniego-Castruita D, Das A, Wang YH, López-Moyado IF, Georges RO, Zhang W, Onodera A, Wu CJ, Lu LF, Hogan PG, Bhandoola A, Rao A

May 14, 2019 Proc Natl Acad Sci U S A

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor

Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG

May 9, 2019 J Phys Chem C Nanomater Interfaces

DNA translocation through hybrid bilayer nanopores

Balasubramanian R, Pal S, Joshi H, Rao A, Naik A, Varma M, Chakraborty B, Maiti PK

May 1, 2019 Nat Commun

Loss of TET2 and TET3 in regulatory T cells unleashes effector function

Yue X, Lio CJ, Samaniego-Castruita D, Li X, Rao A

Apr 26, 2019 Sci Immunol

TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer

Lio CJ, Shukla V, Samaniego-Castruita D, González-Avalos E, Chakraborty A, Yue X, Schatz DG, Ay F, Rao A

Mar 1, 2019 Nature

NR4A transcription factors limit CAR T cell function in solid tumours

Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A